Satiety
The sustained feeling of fullness between meals — distinct from satiation, the signal that ends a single meal.
Nutrition science splits fullness in two: satiation is what stops you mid-meal ("that's enough"), while satiety is what keeps you from wanting the next one. Different hormones run each — stomach stretch and amylin lean toward satiation; GLP-1, PYY, and leptin sustain satiety.
GLP-1 medications strengthen both ends: meals end sooner and the quiet afterward lasts longer, which patients describe as portions shrinking on their own. Food choices still matter — protein and fiber produce more satiety per calorie than refined carbohydrates — so the drugs and the plate work the same lever from opposite sides. Most weight-loss durability lives in this one concept.
This glossary entry is general information, not medical advice, and is written to be consistent with FDA prescribing information and primary trial publications as of its last review. Always consult a licensed healthcare provider for personal medical decisions.
Questions about Satiety? Ask a doctor free.
A licensed doctor can apply this to your health history in a free telehealth consultation — booking takes about two minutes, with programs from $149/month. You're only charged after approval.
Book an Appointment