PCOS (Polycystic Ovary Syndrome)
A common hormonal condition entwined with insulin resistance — where weight treatment often restores cycles and fertility.
PCOS affects a large share of reproductive-age women, combining irregular cycles, androgen excess (acne, hair changes), and polycystic-appearing ovaries — with insulin resistance as the metabolic engine for most. That engine makes weight both harder to lose and more consequential: modest reductions frequently restart ovulation and soften symptoms.
GLP-1 therapy has become a serious PCOS tool off-label, improving weight and insulin sensitivity together; metformin remains a traditional companion. The counseling point that surprises patients: restored ovulation means restored fertility, sometimes abruptly — contraception planning belongs in the conversation from day one, since these medications are contraindicated in pregnancy. Our prescribers screen for PCOS history for exactly these reasons.
This glossary entry is general information, not medical advice, and is written to be consistent with FDA prescribing information and primary trial publications as of its last review. Always consult a licensed healthcare provider for personal medical decisions.
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